P 112 Choroidal melanoma brachytheraphy with iodine 125
نویسندگان
چکیده
suasbourg calme anticilncere " x Paul Strauss Fwpose : llte auhon repwt their short and mean term results in a series of 41 @en& veawd with I 125 brxhylherapy for weal or ciliary bcdy melanomas with minimal follow up of one year. Methods : Among the 47 patients treated wilh I 125 brachylherapy for inlraoadar melanomas ne selected 41 oatienu wkh minimal follow-up of one year. The dose delivered 8(th'apex was 100 gy calculated wilh the USCLA optimization software developped by Melvin Astrahon, USCLA. Results : Tumor stabilization or regression was obtained m 96.5 96 cases, local complications include cataracts in 24 % cases and radiation retinopathy or neumpathy in 30 % Memsltxs has occured in 15 + case.% Conclusion : Dose calculation for delivery IW gy at tumor apex results in in gwd tumor confrol but induces frequenr local complications despile dosimenic optimization. P 113 TITLE : The role of organ-savmg methods in treatment of patients with uwd melanoma. Purpose : To analyse dte efticiency of the system of care for the patient with weal melanoma during last 4 years in St Petersburg. Methods : Selection of patients for norgao-saving treatment in the out-pauent oncosurgay department (surgical ablation, brachytherapy 300 gron the top of the tumor, laser ablation dwapy with a quasicondnous-wave high powered YAG-laser), long-term follow-up. Results : 80 % from 92 patients with malignant weal melanoma have got organ-saving freatment. but in 5 cases the reaper&m was needed. The eyeglobe. was saved in 67 cases, in 42 cases wkh practically useful visual acquity. Lethal ootcomes were observed no more ofw than in enuckation group. Conclusion : The system of organisation of ophthalmological care regarding weal melanoma that we did accept ens-rather high efficiency in organ-saving treatment. flWCCC& The radiotherapy has demonsrrated to be in the last year the most effective conservative trament of chomidnl tumors. External beam irradiation using charged pudcles. as potons and helium ions, has been used preferably for posterior tumors. while bmquitberapy was reserved for honors located anteriorly. in the ciliary body or peripheral chomid. The development of new plaques permill the ueatmem of mo# posteriior lomors of the retina and chomid. S and-We present !he mxdment of 18 intraocular tumors located in the posrerior pole: 16 chomidal melanomas. 1 chomklal metastases and 1 retinoblastoma The tumors ranged from 7.5 to 16 mm in diameter, and from 3.5 to 1.6 in elevation. The location …
منابع مشابه
Experiences of two different modalities in the management of choroidal melanoma in the Asian Indian population
BACKGROUND Choroidal malignant melanoma is a rare intraocular cancer in Asian Indian population. There is a paucity of data from our population comparing iodine 125 (I-125) brachytherapy and enucleation. AIM This study aims to compare two groups of choroidal melanoma patients treated with either I-125 brachytherapy or enucleation in the Asian Indian population. OBJECTIVES To evaluate the lo...
متن کامل[Quality of life in patients with choroidal melanoma].
PURPOSE To determine whether iodine 125 brachytherapy or enucleation is better for quality of life in patients treated for choroidal melanoma. PATIENTS AND METHODS Sixty-five patients with choroidal melanoma were treated with a modified version of VF-14 iodine 125 brachytherapy, enucleation or both. Results of this treatment were then statistically analyzed. RESULTS Statistically significan...
متن کاملClinical and cytogenetic characteristics of choroidal melanoma in Vietnamese sians
Purpose: To report the clinical and cytogenetic characteristics of choroidal melanoma in Vietnamese Asians. Methods: In three Vietnamese Asians with choroidal melanoma, transscleral fine needle aspiration biopsy (FNAB) was performed immediately before Iodine-125 brachytherapy. Biopsy was examined for cytopathology, fluorescence in situ hybridization (FISH) for the centromere of chromosome 3, an...
متن کاملClinical and cytogenetic characteristics of choroidal melanoma in Vietnamese Asians
PURPOSE To report the clinical and cytogenetic characteristics of choroidal melanoma in Vietnamese Asians. METHODS In three Vietnamese Asians with choroidal melanoma, transscleral fine needle aspiration biopsy (FNAB) was performed immediately before iodine-125 brachytherapy. Biopsy was examined for cytopathology, fluorescence in situ hybridization (FISH) for the centromere of chromosome 3, an...
متن کاملThe investigators' perspective on the collaborative ocular melanoma study.
bling times in metastatic malignant melanoma of the uvea: tumor progression before and after treatment. Ophthalmology. 2000;107(8):1443-1449. 8. Clarke M, Collins R, Darby S, et al. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Lancet. 2005;366(9503):2087-2106. 9. Presch...
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ورودعنوان ژورنال:
- Vision Research
دوره 35 شماره
صفحات -
تاریخ انتشار 1995